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In rats, microcephaly can be induced experimentally by giving carcinogens during sensitive periods of embryogenesis. Here, the microcephaly appears to result from necrosis of the neuroblasts lining the ventricles, and from a concomitant reduction in DNA synthesis. The pathogenesis of the microcephaly in our patient and others remains by: 5. Microcephaly is a condition where the head (circumference) is smaller than normal. Microcephaly may be caused by genetic abnormalities or by drugs, alcohol, certain viruses, and toxins that are exposed to the fetus during pregnancy and damage the developing brain tissue.

Nov 01,  · • A microcephalic woman who walked, spoke a few words, and was capable of some self-care, died at age The brain weighed g—the equivalent of that of an infant of eight months' gestation. The remarkable neuropathological features in our case included very small cerebral hemispheres, normal Cited by: 5. Mar 04,  · Microcephaly can be caused by exposure during pregnancy to viruses like Zika, rubella or cytomegalovirus, a herpes virus also known as Kimberly Leonard.

Microcephaly Microcephaly is a medical condition in which the circumference of the head is smaller than normal because the brain has not developed properly or has stopped growing. Microcephaly can be present at birth or it may develop in the first few years of life. Oct 28,  · Microcephaly is a condition in which an individual has a head circumference of 2 SD below the mean. the total brain volume of the year-old would be larger at cc. Brains at 10 years are about % smaller than adult size (Dekaban & Sadowsky, ), suggesting that that brain would grow to an adult size of cc.

Jan 30,  · Microcephaly is a term used to describe an uncommon neurological disorder that is characterized by a substantially smaller head in an infant as compared to the head sizes of other children of same gender and age. Microcephaly is generally caused due to abnormal development of the brain in the womb, or after birth.